无痛的替代肝炎患者的肝活检证明准确和可靠的

StephenW

Study: Fast, painless alternative to liver biopsies for hepatitis patients proves accurate and reliable


DETROIT – A non-invasive alternative to liver biopsy, now the standard method of diagnosing cirrhosis in hepatitis patients, proved very reliable in a national multi-center study including Henry Ford Hospital.

The results of the study are good news for chronic hepatitis B and C sufferers who now often undergo repeated and potentially painful liver biopsies as part of their disease management.

The focus of the research was the French-made FibroScan, which was being used in more than 70 countries worldwide when it received approval by the U.S. Food and Drug Administration in April.

The study is being presented at the annual meeting of the American Association for the Study of Liver Diseases being held in Washington, DC, Nov. 1-5.

In liver biopsy, a sample of tissue is most often collected using a needle inserted through the skin and underlying tissue and into the liver. It is widely regarded as safe, but because it's invasive, carries risks ranging from pain and bleeding, to rare instances of death.

FibroScan replaces liver biopsies with a quick and painless procedure similar to the familiar ultrasound tests long used to diagnose and track pregnancy, as well as internal disease.

It's based on a technology called transient elastography, which measures liver "stiffness" to assess the degree of fibrosis – scarring – and guide ongoing treatment. The scan is performed as an outpatient procedure, taking only about 15 minutes, and providing immediate results on the degree of liver fibrosis.

To confirm the accuracy of FibroScan – already established by research studies in Europe and Asia – the new U.S. research focused on 814 patients with chronic type B and C viral hepatitis.

Each was examined using FibroScan followed by liver biopsy, and the results were compared according to several criteria.

"What we found," said Stuart C. Gordon, M.D., director of the Hepatology section at Henry Ford, who participated in the study, "confirms that FibroScan very accurately assesses for the presence of cirrhosis in patients with both types of chronic viral hepatitis."

The study also noted that the device "exhibits excellent reproducibility," which makes it a "reasonable alternative" to liver biopsy.

StephenW

研究：快速，无痛的替代型肝炎患者的肝活检证明准确和可靠的

底特律 - 现在的标准方法诊断肝硬化肝炎患者肝活检，非侵入性的替代，在全国多中心研究，包括亨利·福特医院证明是非常可靠的。

这项研究的结果是慢性乙型和丙型肝炎患者，现在经常进行重复和潜在的痛苦的肝活检作为他们的疾病管理的好消息。

研究的重点是肝纤维化法国，它被用来在全球70多个国家，当它在4月由美国食品和药物管理局批准。

这项研究被发表在美国协会的年会上被关押在华盛顿特区，11月1-5肝病研究。

在肝活检组织样本，最多收集使用的针插入穿过皮肤及相关组织进入肝脏。它被广泛认为是安全的，但由于它是侵入性的，带有为疼痛和出血，极少数情况下死亡的风险。

肝纤维化取代一个快速和无痛的过程类似于长期用于诊断和跟踪怀孕熟悉的超声波测试，以及内部疾病与肝活检。

它是基于一种技术称为瞬时弹性成像，测量“刚度”肝纤维化程度评估 - 疤痕 - 引导持续治疗。执行扫描为门诊手术，只有约15分钟，并提供立竿见影的效果，对肝纤维化程度。

为了证实肝纤维化的准确性 - 已经在欧洲和亚洲建立了研究 - 美国新的研究主要集中在814例慢性B，C型肝炎。

每个检查肝纤维化跟着肝活检，结果进行了比较，根据几个标准。

斯图尔特C.戈登， MD ，肝脏部分董事在亨利福特，谁参与了这项研究， “我们发现了什么，说：” “确认，非常准确地评估肝纤维化肝硬化的存在两种类型的慢性病毒性肝炎患者“。

该研究还指出，该设备“表现出优异的可重复性， ”这是一个“合理的选择”肝活检。