怀孕吃替诺

林子云

我在网上看到美国有报道78例孕期服用替诺福韦后婴儿有毒性反应；同时还看到有报道孕期服用替诺福韦后婴儿长到1岁时身高和头围比未服用替诺的婴儿小1厘米，各位是怎么看待这两个问题的？这能说明替诺不比替比或拉米在孕期使用更安全吗？

StephenW

回复 林子云 的帖子

Infants born to women who used the anti-HIV drug tenofovir as part of an anti-HIV drug regimen during pregnancy do not weigh less at birth and are not of shorter length than infants born to women who used anti-HIV drug regimens that do not include tenofovir during pregnancy, according to findings from a National Institutes of Health network study. However, at 1 year of age, children born to the tenofovir-treated mothers were slightly shorter and had slightly smaller head circumference — about 1 centimeter each, on average — than were infants whose mothers did not take tenofovir.

The study authors described the findings as reassuring, noting that the study did not identify any serious safety concerns during pregnancy for tenofovir. In combination with other anti-HIV drugs, the drug is the first line of treatment for adults with HIV. The researchers called for additional studies to follow the children as they grow and develop, to identify any potential long term effects of the treatment. Information on Tenofovir and formulations containing tenofovir is available at http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000198/.

出生的婴儿的妇女在怀孕期间使用的抗艾滋病病毒药物泰诺福韦的抗艾滋病病毒药物方案的一部分不重量更轻，在出生时是没有出生的婴儿的妇女使用抗艾滋病毒的药物治疗方案，不较短的长度比包括替诺福韦在怀孕过程中，根据从美国国立卫生研究院网络研究的结果。然而，在1岁以内，与替诺福韦治疗的母亲所生的子女，略短，头围略小 - 各约1厘米，平均 - 比婴儿的母亲没有替诺福韦。

这项研究的作者的调查结果令人欣慰，并指出，这项研究并没有发现任何严重的安全问题，在怀孕期间替诺福韦。结合其他抗HIV药物，这种药物是为成人艾滋病毒感染者的第一线治疗。研究人员呼吁更多的研究遵循的孩子，为他们的成长和发展，以识别任何潜在的长期治疗的效果。泰诺福韦，配方中含有替诺福韦的信息是提供http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000198/。