BI 201335 + BI 207127

StephenW

82% cured without interferon


New data from the largest Phase II interferon-free trial to date, reveal that up to 82 percent of hep C patients achieved a viral cure after just 28 weeks of treatment. These results were shown in specific patients infected with two prevalent types of hep C (genotypes 1a and 1b). These findings were demonstrated in the largest Phase II interferon-free trial to date, with a total of 362 patients, including those patients with advanced liver disease. All patients in the study received treatment with the interferon-free combination of two investigational compounds, the once daily protease inhibitor BI 201335 and the polymerase inhibitor BI 207127, both with and without ribavirin and with varying treatment durations. Of all the patients studied, including those with the hardest to cure type of hepatitis C (genotype-1a non-CC), 68 percent achieved a viral cure after 28 weeks of treatment. Most significantly, up to 82 percent of specific patients with one of the most common HCV types found across Europe and Asia (genotypes-1a CC and -1b), achieved viral cure after 28 weeks of treatment.


82％治愈，无干扰素


最大的第二期干扰素免费试用最新的新数据显示，高达82％的丙肝患者达到病毒治愈后，短短28个星期的治疗。这些结果表明，在具体患者感染丙肝流行的类型（基因型1a和1b）。这些研究结果表明，在最大的二期无干扰素
共362例，其中包括与先进的肝脏疾病的患者。两个研究化合物
无
干扰素组合，每天一次的BI201335蛋白酶抑制剂和聚合酶抑制剂BI207127，都与不同的治疗期间无利巴韦林和所有参与研究的患者接受了治疗。所有患者的研究，包括那些最难治愈丙型肝炎型（基因型1A非CC），68％达到28个星期的治疗后病毒治疗。最显着，高达82％，在欧洲和亚洲（基因型-1A CC-1B），发现最常见的丙型肝炎病毒类型之一的特定患者达到28周的治疗后病毒治疗。

一只臭臭猫

若没把握翻译，可在丁香园求助，以保证帖子的高质量。

StephenW

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谢谢您的建议。我用谷歌翻译(Google Translate).

limi2011321