Hep B virus infections and risk factors among the general population in An

StephenW

Hepatitis B is one of the most common infectious diseases in China. The aim of this study was to determine the prevalence of hepatitis B surface antigen (HBsAg) among the general population and the risk factors associated with HBV infection in Anhui province, China.

Methods: A provincial serosurvey was conducted in four cities, and selected through stratified clustering sampling.

Data on demographics, immunization history, medical history, family medical history, and life history were collected, along with serum tested for HBsAg. Completed surveys were analysed from 8,875 participants.

Results: Overall prevalence of HBsAg was 7.44%.

Using multivariate analysis, older age was a risk factor for HBsAg infection among children younger than 15 years. Among adults 15-59 years old, the risk factors were male gender, a history of surgical operations, at least one HBsAg-positive family member, and non-vaccination.

For adults older than 59 years, the risk factor was a blood transfusion history.

Conclusions: Though Anhui province has already reached the national goal of reducing HBsAg prevalence to less than 1% among children younger than 5 years, there are still several risk factors for HBsAg infection among the older population. Immunization programs should continue to focus on adults, and interventions should be taken to reduce risk factors associated with being infected with Hepatitis B.

Author: Xiaoqing LiYingjun ZhengAdrian LiauBiao CaiDongqing YeFeng HuangXiaorong ShengFuyang GeLiu XuanShun LiJing Li
Credits/Source: BMC Public Health 2012, 12:272

StephenW

乙型肝炎是在中国最常见的传染病之一。本研究的目的是要确定B型肝炎表面抗原（HBsAg）的患病率在普通人群中，与乙肝病毒感染在安徽省，中国有关的风险因素。

方法：省级血清学调查，在四个城市进行，并通过分层聚类抽样选择。

人口统计，免疫史，病史，家族病史，和生命的历史数据进行收集，随着血清测试对乙肝表面抗原。从8,875人参加完成的调查分析。

结果：HBsAg的总患病率为7.44％。

使用多变量分析显示，年龄是其中超过15岁以下儿童乙肝表面抗原感染的危险因素。其中15-59岁的成年人中，危险因素为男性，手术的历史，至少有一个乙肝表面抗原阳性的家庭成员，和非接种。

对于年龄超过59岁的成年人，风险因素是输血史。

结论：虽然安徽省已达到减少HBsAg的患病率超过5岁以下儿童中不到1％的国家的目标，仍然有几个危险因素之间的老年人口为乙肝表面抗原感染。免疫接种计划应继续专注于成人，并应采取干预措施，以减少与B型肝炎感染有关的危险因素

：小青LiYingjun ZhengAdrian LiauBiao CaiDongqing叶风HuangXiaorong ShengFuyang GeLiu XuanShun丽景李
积分/来源：BMC公共健康2012年，12:272