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Association Between Viral Hepatitis and Erectile Dysfunction: A Population-Based [复制链接]

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发表于 2012-3-12 16:45 |只看该作者 |倒序浏览 |打印
http://www.ncbi.nlm.nih.gov/pubmed/22375942
J Sex Med. 2012 Feb 29. doi: 10.1111/j.1743-6109.2012.02663.x. [Epub ahead of print]
Association Between Viral Hepatitis and Erectile Dysfunction: A Population-Based Case-Control Analysis.Chung SD, Keller JJ, Liang YC, Lin HC.
SourceDivision of Urology, Department of Surgery, Far Eastern Memorial Hospital, Ban Ciao, Taipei, Taiwan             Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan             School of Health Care Administration, Taipei Medical University, Taipei, Taiwan             School of Medical Laboratory Sciences and Biotechnology, Taipei Medical University, Taipei, Taiwan.

AbstractIntroduction.  Chronic liver diseases are often accompanied by hypogonadism, testicular atrophy, and a reduction in libido, all of which are factors that may contribute to the development of erectile dysfunction (ED). However, large-scaled studies investigating the association between ED and viral hepatitis are still sparse. Aim.  This study aimed to estimate the association between ED and a prior diagnosis of viral hepatitis using a population-based dataset with a case-control design in Taiwan. Methods.  We identified 6,429 patients with ED as cases and randomly selected 32,145 subjects as controls. We used conditional logistic regression to compute the odds ratio (OR) for having previously received a diagnosis of viral hepatitis between cases and controls. Main Outcome Measure.  The prevalence and odds of having been previously diagnosed with hepatitis B, hepatitis C, a coinfection with hepatitis B and C, and viral hepatitis of other etiology were calculated between cases and controls. Results.  Of the 38,574 sampled subjects, 3,930 (10.2%) had viral hepatitis before the index date; viral hepatitis was found in 900 (14.0%) cases and in 3,030 (9.4%) controls. After adjusting for monthly income, geographic location, hypertension, diabetes, hyperlipidemia, hepatic steatosis, coronary heart disease, obesity, and alcohol abuse/alcohol dependence syndrome, cases were found to be more likely to have prior viral hepatitis than controls (OR = 1.51, 95% confidence interval [CI] = 1.39-1.64, P < 0.001). A much higher proportion of coinfection with viral hepatitis B and C was additionally found among cases (OR = 1.84, 95% CI = 1.72-1.97) than controls. Conclusions.  We conclude that ED was associated with prior viral hepatitis, especially with a coinfection of hepatitis B and C, after adjusting for potential confounders. Chung S-D, Keller JJ, Liang YC, and Lin HC. Association between viral hepatitis and erectile dysfunction: A population-based case-control analysis. J Sex Med **;**:**-**.
© 2012 International Society for Sexual Medicine.

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发表于 2012-3-12 16:46 |只看该作者
本帖最后由 StephenW 于 2012-3-12 17:22 编辑

J性医学。 2012年二月29。 DOI:10.1111/j.1743-6109.2012.02663.x。 [出处提前打印]
病毒性肝炎和勃起功能障碍之间的关联:以人口为基础的病例对照分析。
涌的SD,凯勒JJ,梁远超,林HC。


科,泌尿外科,外科部,远东纪念医院,潘基文的Ciao,台北,台湾临床医学研究所,医学院,国立台湾大学,台北,台湾医务管理学院,台北医学大学,台北,台湾学校医务化验科学及生物科技,台北医学大学,台北,台湾。
抽象

介绍。慢性肝病往往伴有性腺功能低下,睾丸萎缩,性欲减少,所有这些因素可能导致勃起功能障碍(ED)的发展。然而,大型的研究ED和病毒性肝炎之间的关联仍然稀少。目的。本研究旨在评估协会之间的海关和病毒性肝炎的早期诊断,以人口为基础的数据集,在台湾的病例对照设计。方法。我们确定了6,429例有勃起功能障碍的情况下,作为对照组随机选取32145科目。我们用条件Logistic回归计算曾收到病毒性肝炎的诊断病例​​组和对照组之间的比值比(OR)。主要成果的措施。此前已与乙型肝炎,丙型肝炎,乙型肝炎和丙型肝炎合并感染,病毒性肝炎和其他病因诊断的患病率和赔率计算病例组和对照组之间。索引日期前,38574采样科目,3,930(10.2%)的结果有病毒性肝炎,病毒性肝炎900例(14.0%)和3,030(9.4%)控制。调整后的每月收入,地理位置,高血压,糖尿病,高血脂,脂肪肝,冠心病的,肥胖,酒精滥用/酒精依赖综合征,案件被发现的可能性比对照组(OR = 1.51,有事先病毒性肝炎95%信心区间[CI] = 1.39-1.64,P <0.01)。另外一个与乙型和丙型肝炎病毒混合感染的比例要高得多,在案件中发现(OR = 1.84,95%CI = 1.72-1.97)比对照组。结论:我们的结论,ED与前病毒性肝炎,尤其是乙型和丙型肝炎合并感染,潜在的混杂因素调整后。钟的S-研发,凯勒JJ,梁远超,林慧聪。病毒性肝炎和勃起功能障碍之间的关联:以人群为基础的病例对照分析。性别J MED **; **:**  -  **。

©2012年国际社会对性医学。

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发表于 2012-3-12 17:12 |只看该作者

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才高八斗

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发表于 2012-3-12 17:32 |只看该作者
回复 咬牙硬挺 的帖子

受到 ED 我认为你必须要病得很重

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发表于 2012-3-12 20:02 |只看该作者
还是请把握当下再翻译一下吧.
病友交流,仅供参考.
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