血浆也可治疗病毒感染

tonychant

人类将很快会用非正常方式来对付这些威胁人生命的病毒，例如艾滋病毒、SARS病毒、肝炎病毒和流感病毒，因为研究者已经证明了血浆在灭活和阻止腺病毒复制方面的作用。
当暴露于血浆这种非固液气的第四种状态的物质仅仅240秒，病毒实际上都处于非活跃状态，仅仅有百万分之一的病毒仍可复制。
发表在 IOP Publishing's Journal of Physics D的研究表明：应用物理首先关注病毒的学科之一并且研究表明了血浆在除去表皮的细菌和消毒水方面的有效性。
在医院环境中，血浆发生器实质上可以出去手上潜在的依赖于宿主微生物来复制传播的致命病毒。在长期治疗中，血浆也可以直接吸入来治疗肺部病毒感染或者在输血之前除去体外血中的所有病毒。
Max-Planck Institut für extraterrestrische Physik 和 Technische Universit?t München的研究者们专门选择腺病毒这种最难失活的病毒来检测。这种所引起的疾病只能对症处理症状和感染并发症，而不是打击病毒本身。
腺病毒主要引起呼吸系统疾病像肺炎支气管炎，并且很难灭活。整个病毒包埋于蛋白层中，蛋白层使它保持结构稳定和承受适度的热度和PH的升高。
在这项研究中，实验组腺病毒稀释到某种浓度然后暴露于血浆240秒，然后孵化一小时。对照组腺病毒接受了除血浆暴露以外的处理。
两组平行的细胞系分别感染这两种病毒：用血浆处理的实验组腺病毒和对照组腺病毒。为了检测细胞是否被感染，研究者使病毒表达一种蛋白，当某种特殊的光照射的时候，这种蛋白会发出绿色荧光。
然而 令人惊讶的血浆效应背后的确切的机制还不清楚，人们猜想这是血浆与周围空气反应相结合的结果，它会激发类似于细菌感染时免疫系统的反应。
http://www.medicalnewstoday.com/releases/238715.php

StephenW

翻译是不正确的 - 不是"血浆", 是等离子，物质的第四态。

Plasma-Based Treatment Goes Viral
Main Category: Flu / Cold / SARS
Also Included In: HIV / AIDS;  Liver Disease / Hepatitis
Article Date: 07 Dec 2011 - 0:00 PST



Life-threatening viruses such as HIV, SARS, hepatitis and influenza, could soon be combatted in an unusual manner as researchers have demonstrated the effectiveness of plasma for inactivating and preventing the replication of adenoviruses.

When exposed to plasma - the fourth state of matter in addition to solids, liquids and gases - for a period of just 240 seconds, it was found that only one in a million viruses could still replicate - practically all were inactivated.

The study, published in IOP Publishing's Journal of Physics D: Applied Physics, is one of the first to concentrate specifically on viruses and builds on research that has already shown the usefulness of plasma in eradicating bacteria from skin (http://www.iop.org/news/09/november/page_42357.html) and sterilising water (http://www.iop.org/news/11/nov/page_52641.html).

Within a hospital environment, a plasma generating device could realistically rid hands of potentially lethal viruses that relay on a host organism to replicate and spread. In the long-term, plasma could be inhaled directly to treat viruses in the lungs, or applied to blood outside of the body to remove any viruses before transfusion.

The researchers, from the Max-Planck Institut für extraterrestrische Physik and Technische Universität München, specifically chose adenoviruses to examine as they are one of the most difficult viruses to inactivate. Illnesses resulting from this specific virus, for example, can only be managed by treating symptoms and complications of the infection, rather than targeting the actual virus itself.

Adenoviruses predominantly cause respiratory illnesses such as pneumonia and bronchitis and are hard to inactivate as the whole virus is encased in a protein layer, helping it to remain physically stable and tolerate moderate increases in heat and pH.

In this study, the adenoviruses were diluted to specific concentrations and then exposed to plasma for 240 seconds, before being incubated for an hour. A control group of adenoviruses were given the exact same treatment apart from the plasma exposure.

Two separate cell lines were then infected with the two sets of adenoviruses: the ones that were treated with plasma and the control group. To test whether a cell had the virus or not, the researchers programmed the virus to produce a protein that fluoresced green when a specific type of light was shone onto it.

Whilst the exact mechanisms behind the plasma's impressive effects are relatively unknown, it is thought that they are a result of a combination of reactions between the plasma and surrounding air, which create similar species to the ones found in our own immune system when under microbial attack.