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肝胆相照论坛 论坛 学术讨论& HBV English News: Gilead to buy Pharmasset for $11 billion
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News: Gilead to buy Pharmasset for $11 billion [复制链接]

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发表于 2011-11-21 22:26 |只看该作者 |倒序浏览 |打印
If I remember correctly, Pharmasset is also the company that conducted the clinical trials for Clevudine in the USA



(Reuters) - Gilead Sciences Inc struck a deal to buy Pharmasset Inc for about $11 billion in a huge bet on hepatitis C treatments to diversify its portfolio.

Gilead, the world's largest maker of HIV drugs, will pay $137 per share for each Pharmasset share, a whopping 89 percent premium to Pharmasset's Friday closing price.

Pharmasset has been one of the hottest biotech companies, based on the promise of its experimental hepatitis C medicines.

Its shares have soared in the past year on the potential for its oral drugs to create a regimen without interferons, which cause flu-like side effects that lead many patients with the serious liver disease to stop or delay treatment.

Pharmasset has three hepatitis C medicines in clinical trials. Its lead candidate, PSI-7977, recently been advanced into two Phase III studies

Gilead projected the deal would hurt its earnings through 2014. It is expected to close in the first quarter of next year, when Gilead plans to provide further outlook.

Gilead said it had commitments from Bank of America Merrill Lynch and Barclays Capital for financing of the transaction.

Barclays and Bank of America advised Gilead on the deal, while Morgan Stanley advised Pharmasset. Skadden, Arps, Slate, Meagher & Flom LLP is Gilead's legal counsel, while Sullivan & Cromwell LLP is serving as legal counsel to Pharmasset.

(Reporting by Lewis Krauskopf in New York; additional reporting by Anand Basu in Bangalore; Editing by Esha Dey and John Wallace)

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发表于 2011-11-21 22:26 |只看该作者

如果我没有记错,Pharmasset也是该公司在美国进行克拉夫定的临床试验

(路透社) - 吉利德科学公司达成的协议,对丙型肝炎治疗的巨大赌注购买Pharmasset公司约110亿美元,其投资组合多样化。

Gilead公司,世界上最大的抗艾滋病毒药物的制造商,将支付每股137美元,每个Pharmasset份额高达89%Pharmasset的周五收盘价溢价。

Pharmasset一直最热门的生物技术公司之一,其实验丙型肝炎药物的承诺的基础上。

其股价在过去一年中飙升的口服药物,以创建无干扰素疗法,引起类似流感的副作用,导致严重的肝脏疾病许多患者停止或延误治疗的潜力。

Pharmasset已在临床试验中的3个C型肝炎的药物。其领导候选人,PSI-7977,最近已先进到两个三期研究

Gilead公司预计这笔交易将影响到2014年的盈利。预计在明年第一季度结束时,Gilead公司计划提供进一步的前景。

Gilead公司说,它已经从美国美林和巴克莱资本银行为交易融资的承诺。

巴克莱银行和美洲银行就Gilead公司的交易,而摩根士丹利建议Pharmasset。 Skadden,ARPS,板岩,米格和弗洛姆事务所是Gilead公司的法律顾问,而苏利文克伦威尔律师事务所担任法律顾问Pharmasset。

(汇报刘易斯在纽约Krauskopf,阿南德在班加罗尔巴蜀的其他报告; ESHA德伊和约翰华莱士编辑)

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发表于 2011-11-22 09:13 |只看该作者
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yeah, u r right, Pharmasset is the company that develop Clevudine in the USA and Europe.
人在做,天在看,凡事只求做到无愧于心就好!

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发表于 2011-11-22 16:17 |只看该作者
                                                                         

                        [Something rotten about big pharma ]



press release               
                               

                                        Nov. 21, 2011, 6:28 p.m. EST                               

                                AHF: Gilead 'Pillaged AIDS Enough' to Amass $10B Cash for Pharmasset Deal, Yet Refuses HIV Drug Price Cuts                                As thousands of Americans linger on AIDS drug waiting lists for access to lifesaving AIDS medications, Gilead announces $10.4 billion all-cash purchase of rival company, Pharmasset                       

               
       
       
       
                                 
                                             
                           
                           

LOS ANGELES, Nov 21, 2011 (BUSINESS WIRE) ----In 2010, Gilead had over $6.5 billion in AIDS drug sales; now, after reaping record profits on AIDS and as patent expirations loom on HIV treatments, company looks to rival's pipeline for new products and revenue sources                                                       

                           

On the same day Gilead       Sciences announced its eye-popping $10.4 billion all-cash       purchase of rival Pharmasset,       a drug company working on treatments for Hepatitis C, AIDS       Healthcare Foundation (AHF) today chastised Gilead for refusing       further AIDS drug price concessions to help end AIDS       drug waiting lists and address the severe crisis facing the nation's AIDS       Drug Assistance Program (ADAP), a network of federal and state       funded programs that provide life-saving HIV treatments to low income,       uninsured, and underinsured individuals living with HIV/AIDS nationwide.                                                       

                           

"Over the years, Gilead has pillaged AIDS enough to amass over $10       billion in cash to buy Pharmasset outright, but the company is too cheap       to step in and really help end the AIDS drug waiting lists affecting       many hard-hit ADAPs and thousands of vulnerable Americans living with       HIV/AIDS around the country," said Michael Weinstein, President       of AIDS Healthcare Foundation. "This is outrageous. We renew our call on       Gilead and its C.E.O. John Martin to cut prices and increase access to       its lifesaving AIDS medications for ADAPs nationwide."                                                       

                           

According to a Forbes.com story on the purchase, Gilead's medication, "Viread       (tenofovir) or one of the combinations that contain it, is taken by       eight in ten AIDS patients." Gilead's current pricing for ADAP for       its blockbuster HIV/AIDS combination therapy, Atripla (efavirenz &       tenofovir & emtricitabine) is approximately $10,000 per patient, per       year.                                                       

                           

Background on ADAP                                                       

                           

With state budgets stretched thin and increasing numbers of unemployed       workers without health insurance, many states have been forced to cap       enrollment in their AIDS Drug Assistance Programs. As of November 17th,       there are 6,595 individuals on waiting lists to receive lifesaving AIDS       medications in twelve states. Hundreds of patients in need are being       added to the waiting list each week. In addition, thousands more       Americans living with HIV/AIDS have been dropped from the program or       made ineligible to receive medications through ADAP due to stricter       eligibility requirements.                                                       

                           

Nationwide, ADAPs serve over 165,000 people, accounting for one third of       people on AIDS treatment in the U.S. Unfortunately, the need for these       programs expands every year, as more and more people become infected and       diagnosed with HIV/AIDS; each year thousands of newly diagnosed HIV       patients turn to ADAPs because they cannot afford their medicines.                                                       

                           

AIDS       Healthcare Foundation (AHF), the largest global AIDS organization,       currently provides medical care and services to more than 124,000       individuals in 26 countries worldwide in the US, Africa, Latin       America/Caribbean, the Asia/Pacific region and Eastern Europe.  www.aidshealth.org                                                           

                           

SOURCE: AIDS Healthcare Foundation                                                       

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