Nucleoside Analogues - Interfere with the viral DNA polymerase enzyme used for hepatitis B virus reproduction |
Epivir-HBV
(Lamivudine) | Inhibits viral DNA polymerase | GlaxoSmithKline Philadelphia, PA | FDA Approved
1998 |
Hepsera
(Adefovir Dipivoxil) | Inhibits viral DNA polymerase | Gilead
Foster City, CA | FDA Approved
2002 |
Baraclude
(Entecavir) | Inhibits viral DNA polymerase | Bristol-Myers SquibbPrinceton, NJ | FDA Approved
2005
|
Tyzeka
Sebivo (Europe)
(Telbivudine) | Inhibits viral DNA polymerase | Idenix
Cambridge, MA | FDA Approved
2006 |
Viread
(Tenofovir) | Inhibits viral DNA polymerase | Gilead
Foster City, CA | FDA Approved 2008 |
Emtricitabine
(FTC) | Inhibits viral DNA polymerase | Gilead
Foster City, CA | Phase III |