本帖最后由 风雨不动 于 2012-4-14 14:54 编辑
Summary. This study aimed to examine the prevalence of maternal hepatitis B
virus (HBV) infection in the past 10 years and the age- and parity-specific
incidences for evidence of control of HBV infection in the female reproductive
population. We conducted a retrospective cohort study on 58 736 consecutive
pregnant women delivered from July 1998 to June 2008. Maternal HBV status and
demographic data were retrieved from a computerized database for analysis by
year, age, year of birth and parity. A total of 5788 (10.1%) women had HBV
infection, and the annual prevalence was around 10% throughout. When
categorized by maternal age into six 5-year cohorts, the incidence increased
from 6.8% in the <20 years cohort to 10.8% in the 20–24 and 25–29 year
cohorts, then declined to 9.3% in the ≥40 years cohort (P < 0.001). When
categorized by year of birth into 5-year cohorts, the incidence varied from
9.2% for the 1965–1969 cohort to 11.3% in the 1980–1984 cohort, which then
declined to 7.3% in the ≥1985 cohort (P < 0.001). Multiparas had higher
incidence when compared with nulliparas overall (10.5%vs 9.6%, P = 0.001), and
significantly higher incidences for the 25–29 year (P = 0.009), 30–34 year
(P < 0.001) and 35–39 year (P = 0.032) cohorts when analysed by age. In
conclusion, the prevalence of maternal HBV infection remained constant at 10%
for the past decade. The changes in relation to age and parity suggested that
horizontal transmission, probably by sexual contact, had played an important
role in maintaining the same prevalence as reported from Hong Kong 20 years
ago.
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本研究的目的是审查的流行产妇乙型肝炎病毒(乙型肝炎病毒)感染在过去10年的年龄和具体发病率的证据,控制乙肝病毒感染的女性育龄人群。我们进行了回顾性队列研究58736孕妇连续提供从1998-7到的2008-6。产妇乙型肝炎病毒的载量和人口数据来自一个计算机化的数据库分析,年龄,出生年份和奇偶校验。共有5788个(10.1%)妇女乙型肝炎病毒感染,患病率约为10%。分类的产妇年龄为六个5年组距,发病率增加
从20岁组的6.8%,在20–24和25–29年龄组10.8%,40年龄组然后下降到9.3%,的≥队列(<0.001)。 分类按出生年到5年的组距,不同的发病率从1965-1969的9.2%,在1980–1984组11.3%,然后≥1985队列下降到7.3%。经产妇有较高的发病率相比,产妇整体(10.5%比9.6%,磷=0.001),和显着较高的发病率为25–29年(=0.009),30–34年<0.001)和39年(35–=0.032)同伙分析时的年龄。
结论,在过去的十年孕妇乙型肝炎病毒感染的患病率保持在10%。这些变化与年龄和平价的建议水平传播,可能通过性接触,扮演了一个重要作用维持,相同的流行报告从港20年前。
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