经皮肝穿刺活检前的预防性镇痛的临床比比较研究

StephenW

<http://www.docguide.com/prophylactic-analgesia-percutaneous-liver-biopsy-clinical-comparative-study?hash=04301bd4&eid=21056&alrhash=2e06a4-d460252966da8019c5213f6ae197892e>

Source: Eur J Gastroenterol Hepatol  |  Posted 6 days ago
经皮肝穿刺活检前的预防性镇痛的临床比比较研究
Prophylactic analgesia before percutaneous liver biopsy: a clinical
comparative study

Kramskay R, Tansky A, Eisenberg E, Veitsman E, Baruch Y

European Journal of Gastroenterology and Hepatology (Jun 2011)

INTRODUCTION: Liver biopsy remains the gold standard for the diagnosis and
staging of liver diseases. Despite being painful, analgesia before liver
biopsy is usually avoided due to the notion that pain is minor and due to
the concern of masking possible abdominal symptoms. Postbiopsy pain levels
were previously mapped for the purpose of analgesia planning. AIM: To
compare pain and anxiety levels between two prophylactic treatment
regimens, a combination of sublingual tramadol Hcl with oral lorazepam and
oral diazepam only. PATIENTS AND METHODS: One hundred and thirteen
consecutive patients were selected to receive either prophylactic analgesia
with sublingual tramadol Hcl (50 mg) flashtabs and oral lorazepam [(1 mg)
analgesia group (AG), n=56] or oral diazepam (5 mg) alone [nonAG (NAG),
n=57]. Pain and anxiety levels were assessed using Visual Analogue Scale
(1-10) and State Anxiety Inventory, respectively, 30 min before, and 30 min
and 6 h after the biopsy. RESULTS: The groups were comparable with respect
to baseline characteristics. Thirty minutes after the procedure, pain
levels were significantly lower in the AG (mean Visual Analogue
Scale±standard error of the mean, 1.8±0. 3; median=1) compared with the
NAG (3.1±0.3, median=3; P<0.005). Patients in the NAG (13.8%), reported
high pain intensities (>7) compared with the patients in the AG (3.6%;
P=0.09). Six hours after the procedure, pain intensity remained
significantly lower in the AG compared with the NAG (0.8±0.1 vs. 1.5±0.2;
P<0.005). Anxiety levels were comparable. CONCLUSION: Prophylactic
combination of short-acting tramadol and lorazepam is effective, safe, and
can be used routinely before liver biopsy.

StephenW

谷歌翻译
不是100％准确，仅供参考使用。


预防性镇痛前经皮肝穿刺活检的临床
比较研究

Kramskay R，Tansky一个，艾森伯格发送，魏茨曼发送，巴鲁克Ÿ

欧洲胃肠病学和肝病学杂志（2011年6月）

简介：肝活检仍然是诊断的金标准和
肝脏疾病的分期。尽管是痛苦，镇痛前肝
活检通常是可以避免由于概念，疼痛轻微，由于
掩盖可能的腹部症状的关注。 Postbiopsy疼痛水平
以前映射镇痛规划的目的。目的：
比较两个预防性治疗疼痛和焦虑水平
方案，结合口服劳拉西泮和舌下含服曲马多盐酸
仅口服安定。病人与方法：113个
连续的患者，接受预防性镇痛
舌下含服盐酸曲马多（50毫克）flashtabs和口服劳拉西泮（1毫克）
镇痛组（AG），N =56]或口服地西泮（5毫克）单独[nonAG酶（NAG），
N =57]。疼痛和焦虑水平评估采用视觉模拟量表
（1-10）和国家焦虑量表，分别为前30分钟，30分钟
和6 h后活检。结果：各组与尊重相媲美
基线特征。 30分钟，手术后，疼痛
在AG水平显着降低（平均视觉模拟
规模±平均标准误差1.8±0。 3，中位数= 1）比
NAG的（3.1±0.3，中位数= 3，P<0.005）。在NAG的患者（13.8％），报
在AG的患者（3.6％相比，疼痛强度高（> 7）;
P = 0.09）。 6小时手术后，疼痛的强度仍
显着降低相比，在AG的NAG（0.8±0.1比1.5±0.2;
P <0.005）。焦虑水平具有可比性。结论：预防性
短效曲马多和劳拉西泮的结合是有效，安全，
可用于常规前肝活检。