一则英语新闻：台湾原住民肝癌率比汉族低？

sacrifice

最近偶然看到一则新闻：
Several viral factors are associated with disease progression in hepatitis B virus (HBV) carriers. Compared with Taiwanese Han Chinese, Taiwanese aborigines have a higher prevalence of chronic HBV infection and a higher standardized mortality rate of chronic liver diseases but a lower standardized mortality rate of hepatocellular carcinoma (HCC). The aim of this study was to investigate whether aboriginal Taiwanese HBV carriers have more favorable viral factors which reduce the risk for HCC than Han Chinese carriers.Blood samples from 3,488 HBV carriers (1,527 aborigines and 1,961 Han Chinese) were assayed for aminotransferases, hepatitis B e antigen (HBeAg), HBV DNA, and HBV genotype. Aboriginal HBV carriers had a lower HBeAg-positive rate (5.3% vs. 10.2%, P?<?0.0001) and a lower viral load of HBV DNA?>?2,000?IU/ml (27.4% vs. 36.7%, P?<?0.0001) but a higher rate of alcohol consumption (40.0% vs. 19.3%, P?<?0.0001) than Han Chinese carriers. The prevalence of HBV genotype B in aboriginal carriers (92.7%) was significantly higher than that in Han Chinese carriers (72.7%) in all age groups (P?<?0.05). In addition, patients with rare genotype D infections were clustered in a township in southern Taiwan. In conclusion, aboriginal Taiwanese HBV carriers have more favorable viral factors than Han Chinese carriers, which may be partly responsible for the lower standardized mortality rate of HCC in Taiwanese aborigines.





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StephenW

回复 sacrifice 的帖子

I think their genotype being predominately type "B" plays a major role.

springa

和水有关.

zlj1982

才几个原住民，这个我想没什么意义吧