[肝胆速递] 怀孕期间接种疫苗

bigben446

怀孕期间接种疫苗
Vaccination during pregnancy

[肝胆速递] ：怀孕期间接种疫苗是安全的。

Bozzo P, Narducci A, EinarsonA
Canadian Family Physician 57 (5), 555-7 (May 2011)

Question
One of my patients is studying to become a dental hygienist. Owing to the program requirements, she received several vaccinations last week, including measles-mumps-rubella, varicella, and hepatitis B (HB) vaccines, as well as a tetanus booster. However, today a blood test confirmed that she is currently 6 weeks pregnant. What is known about the safety of these vaccines uring pregnancy, and are there any general recommendations for vaccines for women who are planning to become pregnant or who are currently pregnant?

Answer
The combination measles-mumps-rubella vaccine and the varicella vaccine are live attenuated vaccines, and are contraindicated during pregnancy owing to theoretical concerns. However, there is no evidence that there are increased risks of malformations, congenital rubella syndrome, or varicella syndrome attributable to these vaccines. The HB and tetanus vaccines are composed of noninfectious particles or toxoids, and theoretically should cause no increased risk to the developing fetus. In addition, limited observational data also support no increased risk of any adverse pregnancy outcomes; consequently, administration of the HB and tetanus vaccines might be, if indicated, considered during pregnancy.








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bigben446

同时贴一个不同观点的报道

乙肝疫苗接种系列问答(6)：
怀孕期间能不能接种乙肝疫苗？

　　一些女性在婚检后接种乙肝疫苗的过程中发现已经怀孕。乙肝疫苗对妊娠妇女和胎儿安全吗？

　　根据目前国内外大多数的文献报道，乙肝疫苗在妊娠期间使用是安全的。妊娠期间接种2剂或3剂乙肝疫苗后不仅可产生有效的免疫力，保护妊娠期间免受乙肝病毒感染，还能使新生儿获得保护性乙肝抗体。但是，我国曾有乙肝疫苗导致早期妊娠流产的文献报道。因此不建议妊娠期间接种乙肝疫苗。如果乙肝病毒感染者的妻子在未接种乙肝疫苗的情况下已经怀孕，且抗HBs阴性，也不必补种疫苗，只要在孕期避免性生活，孩子出生后立即接种乙肝疫苗同样可以起到预防乙肝病毒感染的作用。但若在接种乙肝疫苗时意外怀孕，也不必终止妊娠，可以继续妊娠。因为到目前为止，除了导致流产外，还没有乙肝疫苗导致胎儿发育异常的报道。

http://ditancaihaodong.blog.sohu.com/172199201.html