Tenofovir HK$86 per tablet, Entecavir HK$110 per tablet

StephenW

http://www.thestandard.com.hk/news_detail.asp?pp_cat=11&art_id=110279&sid=32073678&con_type=1
Drug hope for hepatitis B sufferers

                                Tuesday, April 19, 2011

                                A University of Hong Kong professor hopes to see wider use of an anti-HIV drug to treat hepatitis B, which affects about  8percent of the population.Department of medicine chair professor Lai Ching-lung cited a 2008 overseas study that found Tenofovir, an antiretroviral drug, effectively suppresses the DNA level of the hepatitis B virus.
Prolonged suppression of   the DNA has shown to lessen the risk of cirrhosis and liver cancer - complications that often arise from chronic hepatitis B infection.
Tenofovir is registered with the Hospital Authority, and each tablet costs HK$86.
Lai said another alternative  is Entecavir, an antiviral drug,     which costs HK$110 for each tablet. The study compared the virological response of patients who took Tenofovir with the commonly used drug Adefovir over a period of four years.
More than 80 percent of the 266 patients who took Tenofovir had their virus DNA level suppressed around the 48th   week as compared to about 10 percent of patients who took Adefovir, Lai said.
Hepatitis B carrier Chan Ka- yu, 41, switched to Tenofovir earlier this month after taking Entecavir and Adefovir since last year.
Hepatitis B is 50 to 100 times more infectious than HIV, which can lead to AIDS, Lai added.
SERINAH HO   

StephenW

B型肝炎药物的患者希望

星期二，2011年4月19日

一个香港大学教授希望看到一个更广泛的抗艾滋病病毒药物来治疗乙肝，这影响的人口约8percent。

医学讲座教授赖李金龙处引用了2008年海外研究发现泰诺福韦，一抗逆转录病毒药物，有效地抑制了乙肝病毒DNA水平。

长期抑制的DNA显示，以减少肝硬化和肝癌的风险- 并发症，往往产生慢性乙型肝炎感染。

泰诺福韦登记与医院管理局，每片费用港币86元。

赖说，另一种选择是恩替卡韦，一种抗病毒药物，它的价格为每片港币110元。这项研究比较了谁的病人与常用药物阿德福韦超过四年内泰诺福韦病毒学应答。

超过80266名患者有百分之谁了泰诺福韦其病毒DNA水平上抑制各地的48周相比，谁的病人约10阿德福韦了百分之赖说。

B型肝炎带陈嘉钰，41岁，切换到本月初的Tenofovir服用恩替卡韦和去年以来阿德福韦。

乙型肝炎是50到100倍以上的艾滋病毒，从而导致艾滋病等传染性丽补充说。

SERINA HO

jjf19800212

沙发