咖啡的妙用----肝病患者的福音

kxx136

是不是真的？

高血压

应该是真的，起码有效果

SYKT66

StephenW

是真的.

<http://jech.bmj.com/content/early/2010/08/06/jech.2009.104125.short?rss=1>

J Epidemiol Community Health doi:10.1136/jech.2009.104125

Short report
Moderate coffee consumption reduces the risk of hepatocellular carcinoma in
hepatitis B chronic carriers: a case-control study

Winnie Wing-man Leung1, Suzanne C Ho1,2, Henry L Y Chan3, Vincent Wong3,
Winnie Yeo4, Tony S K Mok4

1School of Public Health and Primary Care, The Chinese University of Hong
Kong, Hong Kong SAR, The People's Republic of China
2Department of Community and Family Medicine, The Chinese University of Hong
Kong, Hong Kong SAR, The People's Republic of China
3Department of Medicine and Therapeutics, The Chinese University of Hong Kong,
Hong Kong SAR, The People's Republic of China
4Department of Clinical Oncology, The Chinese University of Hong Kong, Hong
Kong SAR, The People's Republic of China

Correspondence to
Ms Winnie W Leung, c/o Ms Joyce Leung, 2/F PEC Building, School of Public
Health and Primary Care, Prince of Wales Hospital, Shatin, N.T., Hong Kong;
[email protected]

Accepted 2 June 2010
Published Online First 6 August 2010

Abstract
Background Recent epidemiological studies have reported a dose-dependent
protective effect of coffee on hepatocellular carcinoma (HCC) with risk
reduction ranging from 30% to 80% in daily coffee drinkers compared with
non-drinkers. This study examined whether coffee has a similar protective
effect when consumed in moderate quantities in chronic hepatitis B virus (HBV)
carriers, a group at high risk of developing liver cancer.
Methods A case-control design was employed. 234 HBV chronic carriers (109
cases and 125 controls) were recruited from the Prince of Wales Hospital in
Hong Kong from December 2007 to May 2008. Data collection included review of
medical records and face-to-face interview. Univariate and multivariate
logistic regressions adjusting for age, gender, cigarette smoking, alcohol
use, tea consumption and physical activity were conducted with dose-response
analysis.
Results Moderate coffee consumption significantly reduced the risk of HCC by
almost half (OR 0.54, 95% CI 0.30 to 0.97) with a significant dose-response
effect (χ2=5.41, df=1, p=0.02), reducing the risk for moderate drinkers by
59% (OR 0.41, 95% CI 0.19 to 0.89).
Conclusion The findings provided evidence to support the protective effect of
coffee consumption in moderate quantities in HBV chronic carriers.

StephenW

是真的.

http://www.hivandhepatitis.com/hep_c/news/2010/010810_a.html
Daily caffeine consumption from about 2 cups of coffee was associated with reduced  liver fibrosis, according to results of a study published in the January 2010 issue of Hepatology. The  protective effect persisted after controlling   for age, sex, race, weight, liver disease,  and alcohol intake, though it was more pronounced in people with hepatitis C virus (HCV) infection.   The researchers found, however, that consumption of decaffeinated coffee -- or of caffeine  from sources other than coffee -- was not   associated with reduced fibrosis.