Genotype X/C recombinant (putative genotype I) of hepatitis B virus is

liver411

J Med Virol. 2010 Jun 22;82(8):1327-1333. [Epub ahead of print]

Genotype X/C recombinant (putative genotype I) of hepatitis B virus is rare in
Hanoi, Vietnam-genotypes B4 and C1 predominate.

Thuy PT, Alestig E, Liem NT, Hannoun C, Lindh M.

National Hospital of Paediatrics, Hanoi, Vietnam.

Abstract
There are eight known genotypes of hepatitis B virus, A-H, and several
subgenotypes, with rather well-defined geographic distributions. HBV genotypes
were evaluated in 153 serum samples from Hanoi, Vietnam. Of the 87 samples
that could be genotyped, genotype B was found in 67 (77%) and genotype C in 19
(22%). All genotype C strains were of subgenotype C1, and the majority of
genotype B strains were B4, while a few were B2. The genotype X/C recombinant
strain, identified previously in Swedish patients of indigenous Vietnamese
origin, was found in one sample. This variant, proposed to be classified as
genotype I, has been found recently also by others in Vietnam and Laos. The
current study indicates that the genotype X/C recombinant may represent
approximately 1% of the HBV strains circulating in Vietnam.

J. Med. Virol. 82:1327-1333, 2010. (c) 2010 Wiley-Liss, Inc.
PMID: 20572069 [PubMed - as supplied by publisher]
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