复方鳖甲软肝片疗效如何?

feiyang11

今天到医院做了检查，复方鳖甲软肝片好像没有什么疗效，价格还挺贵，今天停用了，只服用LM。

duguyizhan

能稳定不变 就是成功啊

liver411

他們發表的很多文獻基於國内，而且臨床試葯的過程和數字模糊...

而用英文發表的文獻都是基於仍在動物老鼠身上的實驗而已。他們很會利用國人的民族意識和傳統陳舊概念欺騙錢財，但無疾病。

liver411

http://lib.bioinfo.pl/pmid:17997940
Zhong Xi Yi Jie He Xue Bao. 2007 Nov ;5 (6):651-5 17997940 (P,S,G,E,B)
[Cited?]
[Effect of compound Biejia Ruangan tablet on expressions of connective tissue growth factor mRNA and protein in kidney tissue of rats with adriamycin-induced nephropathy.]
[My paper] Zong-Jiang Zhao, Qi Qiu, Xin-Xue Zhang, Mei-Juan Yang
Objective: To investigate the changes of connective tissue growth factor (CTGF) protein and CTGF mRNA in kidney tissue of rats with adriamycin (ADR)-induced nephropathy and to study the effects of compound Biejia Ruangan tablet (CBJRGT), a traditional Chinese herbal medicine for treatment of liver fibrosis.Methods: A rat model of ADR-induced nephropathy after one-sided nephrectomy was established. Forty-five Wistar rats were randomly divided into 5 groups: normal control group, sham-operated group, untreated group, lotensin-treated group and CBJRGT-treated group. Pathological changes of the kidney tissue were observed by microscopy after 10-week drug administration. The expressions of CTGF protein and CTGF mRNA in the kidney tissue were measured by the methods of immunohistochemistry and in situ hybridization.Results: The expressions of CTGF protein and CTGF mRNA in the normal and sham-operated groups were decreased in the intracytoplasm of glomerular mesangial cells, renal tubular epithelial cells and interstitial cells. Compared with the sham-operated group, the expressions of CTGF protein and CTGF mRNA in the untreated group were markedly increased and the development of renal fibrosis in the untreated group could be observed. CBJRGT could significantly decrease the expressions of CTGF protein and CTGF mRNA, and there was no significant difference between CBJRGT-treated group and lotensin-treated group.Conclusion: CBJRGT may suppress the development of fibrosis through down-regulating the expressions of CTGF protein and CTGF mRNA.

[ 本帖最后由 liver411 于 2008-11-21 15:42 编辑 ]

liver411

Zhongguo Zhong Yao Za Zhi (2004) 29: 62-6.

[Influence of compound biejia ruangan prescription on extracelluar matrix in bleomycin ind

DW Zhang, JF Wang, JZ Niu, MJ Yang, LQ Wang, H Jin, LQ Liu, BH Gao

OBJECTIVE: To study the influence of compound Biejia Ruangan Prescription (CBRP) on extracelluar matrix in bleomycin induced pulmonary fibrosis rats. METHOD: 54 male Sprague-Dawley rats were randomly divided into 6 groups (9 rats in each group). Rats in the model control group, positive medicine group, and high, moderate and low CBRP groups were injected with bleomycin A5 by trachea, and rats in sham-model control group with same volume normal saline. 29 days after the injection, CBRP solution of different dosages (1.4 g x kg(-1), 0.7 g x kg(-1), 0.35 g x kg(-1)) was respectively given to rats in the high, moderate and low CBRP group by gavage, while equal volume of normal saline was given to those in the sham-model control group and model control group, and an equal volume of prednisone (0.56 mg x kg(-1)) was given to those in positive medicine control group. On the 80th day, the levels of III-collagen, IV-collagen, laminin and hyaluronic acid in the serum were determined, the determination of hydroxyproline in lung homogenates was analyzed, and the right lung was incised to make pathological sections which were stained with Hematoxylin-Eosin (HE) and Masson staining for pathological diagnosis. RESULT: CBRP could decrease the levels of III-collagen, IV-collagen, laminin and hyaluronic acid in the serum. CONCLUSION: CBRP may play its therapeutic role by leveling down the content of extracellular matrix in rats with pulmonary fibrosis induced by Bleomycin A5.

吃药啥时停

我用复方鳖甲软肝片2年半，并结合抗病毒治疗有2年时间DNA=0,开始有结节，据说多的不计其数，用到一年半时，结节看不见了。
最近，B超说结节有出现了，有六MM,我怀疑是吃的其它东西（现在的食品危险太大）造成的，现在还再吃复方鳖甲软肝片。
我的观点，复方鳖甲软肝片有效，但是必须在DNA=0（不为0时，病毒不断破坏效果可能受影响）时，长时间治疗才能显现，另外，该药可以帮助消化，和改善面色。这是我的体会，希望对你有帮助。

cuitian

绝对不管用，老公吃了三个月最后还是手术治疗，一点用也不管，我觉得抗病毒是关键，其次是心理也很重要

liver411

原帖由 吃药啥时停 于 2008-11-23 20:12 发表
我用复方鳖甲软肝片2年半，并结合抗病毒治疗有2年时间DNA=0,开始有结节，据说多的不计其数，用到一年半时，结节看不见了。
最近，B超说结节有出现了，有六MM,我怀疑是吃的其它东西（现在的食品危险太大）造成的，现在还再吃复方鳖甲软 ...

問題是根本沒有對照組科研的文獻，試葯數據，比如：吃的，不吃的，真實的隨機選樣，雙盲的實驗，而且在其它國際上任何一個試驗室/試葯單位都應該可重復，結果也應該一樣...它若是能把結節吃掉，哈哈，302醫院的發明也拿了獎，頭像也豎在日内瓦WHO總部了。可能麽？這麽多年了。別閙了。

liver411

原帖由 lywylwl 于 2008-11-12 12:10 发表
楼主你好，我是大三阳，抗病毒治过一段，后停药。这两三年，一直在吃复方鳖甲软肝片，别的药都没吃，B超显示，纤维化没有再发展，而且病毒数量在下降。现在治肝没有特效药，希望楼主不要悔心，慢慢地调养。九阴真肝说地很好：能阻断和延缓 ...

如果有停掉拉米后吃鱉殼子粉和不吃的對照；不用拉米，單獨吃/不吃鱉殼子粉的對照才好説明。

實際上，憋殼子粉末的成分不會比你自己腳趾甲，手指甲的成分差到那裏去。（鱉龜甲殼的主要成分是角質層，鈣質；指甲成分為角質層，也含鈣；二者也都含一點蛋白質-有機物質，角質層=死去的細胞）吃這個不如好好喝牛奶/豆漿。

wer333

啊？茫然。。。。。。。。。。