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https://www.caa.co.uk/Aeromedica ... Disease/Interferon/
UK Civil Aviation Authority
英国民航局
Interferon
Interferon is used for the treatment of active Hepatitis B and C, HIV/AIDs and Multiple Sclerosis.
Interferon is widely documented to have a large number of side-effects. The majority of these side-effects are incompatible with safely undertaking flight duties.
Commonly experienced side-effects include: nausea, vomiting, dyspepsia, diarrhoea, raised serum amylase and lipase, headache, fatigue, dizziness, sleep disturbances; less commonly, thrombocytopenia, rash, alopecia1.
Interferon is also associated with psychiatric health problems including an increased risk of suicide, although some authors are not sure whether this is due to the medication or the underlying disease2. Hoofnagle and Seep noted that side-effects occurred in virtually all patients treated with peginterferon and ribavirin3.
A study published in AIDS Care in 2007 reported that a large number of patients treated with interferon developed neuropsychiatric side effects. All those affected reported that they became symptom free after cessation or completion of treatment4.
Therefore a requirement for, or treatment with, Interferon is disqualifying for aeromedical certification.
干扰素
干扰素用于治疗活动性乙型和丙型肝炎,HIV / AID和多发性硬化症。
干扰素被广泛记录为具有大量副作用。这些副作用中的大多数与安全承担飞行职责是不相容的。
常见的副作用包括:恶心,呕吐,消化不良,腹泻,血清淀粉酶和脂肪酶升高,头痛,疲劳,头晕,睡眠障碍;少见的是血小板减少症,皮疹,脱发1。
干扰素还与精神健康问题有关,包括自杀风险增加,尽管一些作者不确定这是由于药物还是潜在疾病引起的2。 Hoofnagle和Seep指出,几乎所有接受聚乙二醇干扰素和利巴韦林治疗的患者均出现副作用。
2007年发表在AIDS Care上的一项研究报告说,大量接受干扰素治疗的患者出现了神经精神方面的副作用。所有受影响的人都报告说,他们在戒断或完成治疗后无症状4。
因此,对干扰素的要求或进行的治疗均不符合航空医学认证的条件。 |
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