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Assessment of HCC Risk in Patients with Chronic HBV (REACH, PAGE-B, and Beyond)
Terry Cheuk-Fung Yip, Lilian Yan Liang & Grace Lai-Hung Wong
Current Hepatology Reports volume 19, pages285–292(2020)Cite this article
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Abstract
Purpose of Review
To provide an updated overview on the current status of risk prediction scores for hepatocellular carcinoma (HCC) in patients with chronic hepatitis B virus infection.
Recent Findings
More HCC risk scores have been developed, validated, and optimized (e.g., with liver stiffness measurement) in different patient and ethnic groups. Risk scores for treated patients with high negative predictive values would be able to identify patients who may not need HCC surveillance anymore as their HCC risk has been reduced by antiviral therapy.
Summary
Current HCC risk scores can accurately predict HCC in specific populations, in both treatment-naive patients and those receiving antiviral therapy. Different levels of care and different intensities of HCC surveillance should be offered according to the risk profile of patients. |
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