UT西南大学展示便携式供体肝脏系统的功效

StephenW

UT Southwestern Demonstrates Efficacy of Portable Donor Liver System
Healio Gastroenterology, October 2018

UT Southwestern announced its participation in the Liver PROTECT trial of a portable system designed to keep livers warm and blood circulating prior to liver transplantation, according to a press release.

“It’s like a virtual transplant,” Malcolm MacConmara, MD, from UT Southwestern’s department of surgery and lead researcher of the Liver PROTECT study, said in the release. “By putting the liver on the machine, we can truly approximate the conditions of the body. We provide oxygen, blood and nutrition to the liver and watch how it functions before the patient receives the organ.”

According to the release, the portable Organ Care System (TransMedics) is approximately the size of a shopping cart. The interior design connects the donor liver to tubes that infuse the organ with blood.

In a recent transplant case, a 59-year-old patient with liver failure related to cirrhosis and liver cancer underwent transplant at UT Southwestern with a liver transported from a local donor hospital. The patient tolerated the surgery, was removed from the ventilator at the end of the procedure and continued to demonstrate rapid recovery with discharge 3 days posttransplant.

“The longer a liver sits on ice, the more likely it is to have problems after transplant. The liver will become unusable if it has been stored for too long,” Parsia Vagefi, MD, from UT Southwestern and lead surgeon of the recent case’s surgery team, said in the release. “With many patients waiting for organs, this new way of treating organs may expand the number of donated livers that can be used for transplant.”

Reference: www.utsouthwestern.edu

StephenW

UT西南大学展示便携式供体肝脏系统的功效
Healio Gastroenterology，2018年10月

根据一份新闻稿，UT西南大学宣布参与肝脏PROTECT试验的便携式系统，该系统旨在使肝脏移植前肝脏保持温暖和血液循环。

“这就像虚拟移植一样，”来自UT西南大学外科学系和肝脏PROTECT研究首席研究员的Malcolm MacConmara博士在发布会上说。 “通过将肝脏放在机器上，我们可以真实地接近身体的状况。我们为肝脏提供氧气，血液和营养，并在患者接受器官之前观察其功能。“
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根据该发布，便携式器官护理系统（TransMedics）大约相当于购物车的大小。室内设计将供体肝脏连接到向器官注入血液的管道。

在最近的移植病例中，一名患有肝硬化和肝癌相关​​肝功能衰竭的59岁患者在UT西南部接受了移植手术，并从当地捐赠医院运送了肝脏。患者对手术耐受，在手术结束时从呼吸机中取出，并继续显示移植后3天放电迅速恢复。

“肝脏坐在冰上的时间越长，移植后出现问题的可能性就越大。如果肝脏储存时间过长，肝脏将无法使用，“来自UT Southwestern的医学博士Parsia Vagefi和近期病例手术团队的首席外科医生在发布时表示。 “由于许多患者等待器官，这种治疗器官的新方法可能会扩大可用于移植的捐赠肝脏的数量。”

参考：www.utsouthwestern.edu