10月31日再次检测,依旧为10的3次方。所以判断变异
this is the drug resistance test.
Hi. You case is really complex.
LMV resistance: add TDF (add ADV if TDF not
available);
● ADV resistance: it is recommended to switch to TDFif available AND add a second drug without crossresistance.
If an rtN236T substitution is present, add
LMV, ETV, or LdT or switch to TDF plus emtricitabine.
If an rtA181V/T substitution is present, it is
recommended to add-on ETV or to switch to TDF
plus ETV or TDF plus emtricitabine (as a single
tablet: Truvada);
From:
Hepatitis B Virus Resistance to Nucleos(t)ide Analogues
REVIEWS IN BASIC AND CLINICAL GASTROENTEROLOGY
GASTROENTEROLOGY 2009;137:1593–1608
You should do the following:
1. Double check 拉米变异 ]阿德变异. Just to make sure.
2. You should read the paper (Hepatitis B Virus Resistance to Nucleos(t)ide Analogues).
3. Find a really good doctor to present you whole case. (找老王) 老王 is not a good doctor, in my opinion. 老王 is alway boasting to put his patient on 拉米, which is against the update treatment guide.
you CAN NOT USE 恩替卡韦 if you have LAM resistance.
I am a HBVer in US. I am not a doctor. My advices are for you reference only.
10月31日再次检测,依旧为10的3次方。所以判断变异
this is NOT the drug resistance test.
Hi. You case is really complex.
LMV resistance: add TDF (add ADV if TDF not
available);
● ADV resistance: it is recommended to switch to TDFif available AND add a second drug without crossresistance.
If an rtN236T substitution is present, add
LMV, ETV, or LdT or switch to TDF plus emtricitabine.
If an rtA181V/T substitution is present, it is
recommended to add-on ETV or to switch to TDF
plus ETV or TDF plus emtricitabine (as a single
tablet: Truvada);
From:
Hepatitis B Virus Resistance to Nucleos(t)ide Analogues
REVIEWS IN BASIC AND CLINICAL GASTROENTEROLOGY
GASTROENTEROLOGY 2009;137:1593–1608
You should do the following:
1. Double check 拉米变异 ]阿德变异. Just to make sure.
2. You should read the paper (Hepatitis B Virus Resistance to Nucleos(t)ide Analogues).
3. Find a really good doctor to present you whole case. (找老王) 老王 is not a good doctor, in my opinion. 老王 is alway boasting to put his patient on 拉米, which is against the update treatment guide.
you CAN NOT USE 恩替卡韦 if you have LAM resistance.
I am a HBVer in US. I am not a doctor. My advices are for you reference only.