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Recent data have shown that measuring both HBsAg and HBV
395 DNA levels provides more accurate means of determining inactive carrier status than
396 either marker alone [3, 15]. Although these data require verification, they suggest that
measurement of HBsAg levels, along with HBV DNA levels, may be useful in monitoring
patients during the natural course of HBV infection, to distinguish between those
patients with active disease who may benefit from therapy and those who are inactive
carriers, and so do not require treatment [3,15]. Levels of HBsAg that appear to be
helpful for differentiating inactive from active disease are in the range of 1000 to 2000
IU/mL [3,15]. Again, these clinically relevant levels fall into the linear range covered by
the Elecsys HBsAg II quant assay. |
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