我英文并不太好，但自己是HBV慢性的患者，知道大家的痛苦，所以尽力把文章翻出来，如果有错误请大家指正，不为别的，只为了我们自己的未来。
Cost of Chronic Hepatitis B Infection in the United States.
慢性乙肝在美国的花费
Journal of Clinical Gastroenterology. Chronic Hepatitis B from a Global
Perspective: Epidemiology and Costs of Illness. 38(10) Supplement
3:S144-S147, November/December 2004.
临床肠胃病学期刊/全球视角下的慢性乙肝：流行病学和疾病的费用2004年11/12月增刊
Lee, Todd A. PharmD, PhD *+++; Veenstra, David L. PharmD, PhD [S]; Hloeje,
Uchenna H. MD, MPH ; Sullivan, Sean D. PhD [S]
以上是作者吧，我就不翻了。
Abstract:
Goals: To estimate the direct medical costs associated with chronic
hepatitis B (CHB) infection in the United States.
摘要：
目标：评估慢性乙肝传染病在美国的直接医疗费用
Background: Approximately 240,000 new cases of hepatitis B infection occur
annually in the United States. There are estimated to be 1.25 million
sufferers of CHB in the United States. However, the economic impact of these
infections has not been well studied.
背景：美国每年大约有近24万人感染乙型肝炎的新病例出现。据估计，美国大概有125万
慢性乙型肝炎患者。但是这些传染病所引起的经济影响却一直没有人研究过。
Study: We conducted a retrospective cohort analysis using administrative
healthcare claims data to estimate costs for six health states associated
with CHB infection. The six states were as follows: 1) CHB, 2) compensated
cirrhosis, 3) decompensated cirrhosis, 4) liver transplantation, 5)
transplant care >12 months following transplant, and 6) hepatocellular
carcinoma. Patients in each health state were identified using diagnostic
and procedure codes, and their utilization was tracked during their time in
that health state. To estimate costs, we used reimbursed amounts and
adjusted to year 2000 US$.
研究：我们利用医疗行政方面提供的数据来进行了一次回顾性的群体分析。通过这个分析我们可以评估与慢性乙肝感染相关的六种病情状况下的费用：1）慢性乙型肝炎，2）代偿肝硬化
3）代谢失调肝硬化，4）肝移植，5）移植后12个月后的护理，6）肝癌。每种病情状况
下的病人都用诊断流程编码来识别，并且病人在每种病情状况下的花费都在相应的时间内被记录下来。为评估费用，我们统计了返款金额并且调整为每年2000美元。
Results: Average annual costs for patients in each health state were as
follows: CHB, $761; compensated cirrhosis, $227; decompensated cirrhosis,
$11,459; liver transplant, $86,552; transplant care >12 months following
transplant, $12,560; and hepatocellular carcinoma, $7,533. Medications
contributed the largest proportion of costs in CHB and compensated cirrhosis
disease states, while hospitalizations were the largest cost component in
the other health states.
结果：每种病情下的病人平均每年的开销如下：慢性乙肝 761美元，代偿肝硬化 227美元，
代谢失调肝硬化 11，459美元，肝移植 86，552美元，肝移植12个月后的护理 12，560美元，
肝癌 7，533美元。其中，药物费用占了慢性乙肝和代偿肝硬化两种病情下的大部分开销。
而其它病情下的住院治疗费用占了大部分开销。
Conclusions: This analysis provides estimates of the annual costs of
complications of hepatitis B infection in the United States. The most
progressive health states were associated with significantly higher costs.
结论：这个分析提供了乙型肝炎传染病在美国每年的花费评估。大多数病情发展的
情况下总伴随着明显的更高的费用开销。
[此贴子已经被作者于2004-12-26 21:22:38编辑过] | 
发表于 2004-12-11 04:59
