脾脏硬度-脾脏大小与血小板比率风险评分作为乙型肝炎病毒相关肝硬化患者食管静脉曲张的无创预测因子
Young Seo Cho 1 , Sanghyeok Lim 2 , Yongsoo Kim 1 , Min Hee Lee 2 , Seo-Youn Choi 2 , Ji Eun Lee 2
隶属关系
隶属关系
Spleen stiffness-spleen size-to-platelet ratio risk score as noninvasive predictors of esophageal varices in patients with hepatitis B virus-related cirrhosis
Young Seo Cho 1 , Sanghyeok Lim 2 , Yongsoo Kim 1 , Min Hee Lee 2 , Seo-Youn Choi 2 , Ji Eun Lee 2
Affiliations
Affiliations
1
Department of Radiology, Hanyang University Guri Hospital, Hanyang University College of Medicine, Gyeonggi-do, Republic of Korea.
2
Department of Radiology, Soonchunhyang University Hospital Bucheon, SoonChunHyang University College of Medicine, Gyeonggi-do, Republic of Korea.
PMID: 35623071 DOI: 10.1097/MD.0000000000029389
Abstract
This study was conducted to evaluate the predictive value of spleen stiffness-spleen size-to-platelet ratio risk score (SSPS) as a noninvasive predictor of esophageal varices (EVs) and to compare it with others.In this retrospective study, from April 2017 to October 2018, a total of 65 patients with hepatitis B virus-related cirrhosis who underwent the liver and spleen stiffness (LS, and SS) measurements by 2 dimensional-shear wave elastography and endoscopic evaluation for EVs were enrolled. Liver stiffness-spleen size-to-platelet ratio risk score (LSPS) and SSPS were calculated. The prognostic values were assessed by the area under the receiver operating characteristic curve (AUC).Twenty-six patients had no EV on endoscopy. Among 39 patients who had EVs, 12 patients had high risk EVs. The AUCs of the LS value, SS value, LSPS, and SSPS for predicting EVs were 0.72, 0.77, 0.80, and 0.85, respectively. The AUCs of the LS value, SS value, LSPS, and SSPS for predicting high-risk EVs were 0.55, 0.78, 0.67, and 0.80, respectively. SSPS had the highest specificity, at 96.15%, for predicting EVs.SSPS may be beneficial to exclude from having EVs and it is expected that the frequency of performing endoscopies for screening EVs can be reduced.