Is Exercise Beneficial and Safe in Patients with Cirrhosis and Portal Hypertension?
Authors
Authors and affiliations
Elliot B. TapperRoberto Martinez-Macias Andres Duarte-Rojo Email author
Elliot B. Tapper
1
Roberto Martinez-Macias
2
Andres Duarte-Rojo
2 Email author
1.Division of Gastroenterology and HepatologyUniversity of MichiganAnn ArborUSA
2.Division of Gastroenterology and HepatologyUniversity of Arkansas for Medical SciencesLittle RockUSA
Portal Hypertension (J Gonzalez-Abraldes and E Tsochatzis, Section Editors)
First Online: 02 June 2018
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Part of the following topical collections:
Topical Collection on Portal Hypertension
Abstract
Purpose of Review
In spite of the many health benefits attributed to exercise, reports summarizing the literature in patients with cirrhosis are scarce. We aimed to provide a comprehensive review focusing on potential safety considerations in cirrhosis.
Recent Findings
Diminished exercise capacity in patients with cirrhosis worsens their prognosis before and after liver transplantation. Exercise poses unique challenges in this population, raising questions of safety—worsening portal hypertension and malnutrition—and efficacy. In this review, we show that the balance of evidence supports supervised exercise programs with demonstrable benefits with respect to portal pressure, functional capacity, and muscle mass indexes. There are also benefits regarding their emotional function and perceived general health. Key to interpreting the benefits and risk profile of exercise is the impact of non-selective beta-blockage.
Summary
Patients with cirrhosis, with or without portal hypertension, should receive an exercise prescription as part of their standard of care. However, some standard safety recommendations should be universally followed.
Keywords
Hepatic venous portal gradient Cardiopulmonary endurance Aerobic fitness Frailty Sarcopenia Preparticipation 作者: StephenW 时间: 2018-8-8 10:29
肝硬化和门脉高压患者的运动是否有益和安全?
作者
作者和附属机构
Elliot B. TapperRoberto Martinez-Macias Andres Duarte-Rojo电子邮件作者
Elliot B. Tapper
1
罗伯托马丁内斯 - 马西亚斯
2
Andres Duarte-Rojo
2电邮作者