虽然母乳中可检出乙肝表面抗原，[46]母乳喂养还没有被证明能增加传播的危险性比奶瓶喂养。一项研究评估了147个乙肝病毒携带者母亲所生的婴儿表现出[47,48]谁是正确的免疫母乳喂养的新生儿[4,5]母乳喂养可以开始母乳喂养和婴儿慢性乙型肝炎感染的发展之间没有关联。只要婴儿出生免疫球蛋白和疫苗接种首剂。对于谁留在抗病毒治疗产后的母亲，母乳喂养一般不会被推荐。[5]所知不多核苷/核苷酸类似物分泌到母乳哺乳的婴儿在药物暴露程度有关。由Van等人[49]研究表明，母乳含有较低水平相比，TDF的母亲服用TDF与母体血液中。研究表明，不可能有任何生物影响哺乳婴儿。但是，婴幼儿用药的安全性尚未确定。
Although HBsAg can be detected in breast milk,[46] breastfeeding has not been shown to increase the risk of transmission compared with bottle feeding. A study evaluating 147 infants born to HBV-carrier mothers showed no association between breastfeeding and the development of CHB infection in the infants.[47,48] Neonates who are correctly immunized may be breastfed.[4,5] Breastfeeding can be started as long as the infant has received HBIG and the first dose of vaccination at birth. For mothers who remain on antiviral therapy postpartum, breastfeeding has generally not been recommended.[5] Not much is known regarding the extent of drug exposure to the infant during breastfeeding as nucleoside/nucleotide analogues are excreted into the breast milk. A study by Van et al[49] showed that breast milk contained lower levels of TDF compared with maternal blood in mothers taking TDF. The study suggested that there was unlikely any biological effects in the nursing infant. However, the drug safety for infants has not been established. 作者: 2011plan 时间: 2013-9-3 20:43
