标题: Editorial: Measurement of HBsAg Concentration During Antiviral Therapy of Hepati [打印本页] 作者: StephenW 时间: 2011-10-8 22:37 标题: Editorial: Measurement of HBsAg Concentration During Antiviral Therapy of Hepati
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Am J Gastroenterol. 2011 Oct;106(10):1774-6. doi: 10.1038/ajg.2011.263.
Editorial: Measurement of HBsAg Concentration During Antiviral Therapy of
Hepatitis B: Who, When, and Why.
Perrillo R.
Source
Hepatology Division, Baylor University Medical Center, Dallas, Texas, USA.
Abstract
The measurement of hepatitis B surface antigen (HBsAg) concentration in
serum is now under evaluation in treatment trials for hepatitis B. HBsAg
kinetics differ during interferon and nucleoside analog treatment. A rapid
decline in HBsAg concentration during interferon therapy has been
associated with a higher chance for sustained virological response. By
contrast, a much slower decline often occurs during nucleoside analog
therapy and limits the ability of this test to be a useful prognostic
indicator during the first year or two of treatment.