Siemens Healthcare Diagnostics has introduced its second generation in-vitro immunoassay for the qualitative detection of Hepatitis B surface antigen (HBsAg) in human serum and plasma (EDTA, heparin, citrate) using the ADVIA Centaur® and ADVIA Centaur® XP systems.
西门子医疗诊断公司推出了第二代 体外 免疫之定性检测,对人血清和血浆中的乙型肝炎表面抗原(EDTA的,肝素,柠檬酸)(HBsAg), 应用ADVIA®和ADVIA Centaur
® XP系统。
"The new ADVIA Centaur HBsAgII assay offers leading analytical and clinical sensitivity to common HBsAg subtypes, resistance to HBsAg a-determinant mutations and excellent specificity, combined with all the productivity benefits of ADVIA Centaur immunoassay systems," states Sarah Holt, Marketing Manager for Infectious Diseases at Siemens Healthcare Diagnostics.
The new HBsAgII assay will replace the existing HBsAg assay on the ADVIA Centaur systems. It can be used in conjunction with other serological and clinical information to diagnose individuals with acute or chronic Hepatitis B infection. The assay may also be used to screen for Hepatitis B infection in pregnant women to identify neonates at risk of acquiring Hepatitis B during the perinatal period.
Currently two billion people worldwide are infected with the Hepatitis B Virus (HBV) and an estimated 600,000 people die each year due to acute or chronic consequences of this disease especially in Asia and Africa.* It can be easily treated and healthy adults that are infected can recover with the result of lifelong immunity. Carriers of HBV can remain highly infectious and are a potential source of new infections. The chronically infected may suffer serious health consequences such as high risk of liver cirrhosis, liver cancer and may require a liver transplant as a last resort. SOURCE: Siemens Healthcare Diagnostics 作者: StephenW 时间: 2011-5-26 06:09
[Stephen]纠正我,如果我错了。我认为雅培系统是完全自动的,所以即使稀释是必需的,它会用机器做了?
Correct me if I am wrong. I thought the Abbott system is completely automatic, so even if dilution is required, it will be done by machine?
[Stef2011]不是. 雅培在小范围 0.1-250iu/毫升,当然没慢性乙肝患者人低如250iu/ml
乙肝表面抗原,一旦100-300iu/ml接近清除.
在比萨(Pisa, Italy)研究员告诉我,技术人员可以用管道的时候
犯错,因此HBsAg的水平可以有所不同,变化约500iu/ml.
No. Abbott has a small range 0,1-250iu/ml and of course no cronic carrier has such low hbsag as 250iu/ml, once 100-300iu/ml is reached clearance is close.
the researcher in pisa told me that technicians can do mistakes with the pipe sometimes so the hbsag level can vary of about 500iu/ml
[StephenW]稀释必须由人做吗?
Or the dilution must be done by human?
[Stef2011]稀释必须由人做. 事实上,许多实验室都这么懒,仅仅报告效果为“>250iu/ml" 因为他们不想管,并采取愚蠢的稀释。我觉得现在有些技术员
是如此无知使用自动的检测,有时我们知道的比他们更多。
Dilution is required by human, in fact many labs are so lazy to give result as >250iu/ml just because they don't want to take the pipe and make the stupid dilution.I think nowadays some techs are so ignorant using automatic assays that sometimes we know more than them.
[StephenW]罗氏的系统,它是全自动的吗?
The Roche's system, is it automatic?
[Stef2011]是的,范围优越,0-52000iu/ml, 没有稀释.
yes and the range is superior getting to 52000iu/ml with no dilution
[StephenW]你知道新的西门子系统?
Do you know anything the new Siemen system?
[Stef2011]在我镇医院使用它,因为它是乙肝表面抗原变异覆盖最好的,他们收集捐献的血液,所以因为我觉得他们使用这个新的西门子系统。
the hospital in my town took it because it is the best as coverage of hbsag mutants, they collect donated blood so i think they changed architect because of this.